To get started more quickly, you can adopt an existing keyboard layout. You will benefit from the experience of other layout designers to maximise the typing speed and comfort.

• ISRT layout:
  • https://keyboard-design.com/letterlayout.html?layout=isrt.en.ansi
• RSTHD layout
  • https://xsznix.wordpress.com/2016/05/16/introducing-the-rsthd-layout/
• APTv3 layout
  • https://github.com/Apsu/APT#aptv3-layout
• Nerps layout
  • https://www.reddit.com/r/KeyboardLayouts/comments/tpwyjc/sertain_nerts_nerps_low_redirect_low_sfb_low/
• Seniply layout
  • https://stevep99.github.io/seniply/

A site with a list different keyboard layouts based on ANSI QWERTY: https://www.keyboard-design.com/best-layouts.html